I can guarantee that Homelander won't judge her for going on a murder spree. If anything, he'll be like "yeah, I hear that, sometimes you need to murder people who are annoying you and you shouldn't feel bad about it!"

He'd also respect her just barging up and demanding his time and attention. Yeah, let's talk this out! Join him at his Kiddie Pool of Truth, have a beer, and talk about murder!